Beta-glucan is a fiber-type complex sugar (polysaccharide) derived from the cell wall of
baker’s yeast, oat and barley fiber, and many medicinal mushrooms, such as maitake. In their natural states, yeast and
mushrooms contain a mixture of beta-1,3-glucan and beta-1,6-glucan. Oats and barley contain a
mixture of beta-1,3-glucan and beta-1,4-glucan. In addition to purified beta-1,3-glucan from
these sources, you may see products listed as beta-1,3/1,6-glucan in the case of yeast-derived
products and as beta-1,3/1,4-glucan when derived from oats. Similar (if not identical)
properties have been shown for beta-glucan-rich extracts and purified beta-glucan derived from
oats, baker’s yeast, and mushrooms.
Where is it found?
Beta-glucan is found in the cell walls of many yeast and cereal fibers, such as oats,
wheat, and barley. As a dietary
supplement, beta-glucan is available in liquid form as well as in capsules and tablets.
Beta-glucan has been used
in connection with the following conditions (refer to the individual
health concern for complete information):
Who is likely to be deficient?
Because beta-glucan is not an essential nutrient, deficiencies do not occur.
How much is usually taken?
For lowering cholesterol levels, the amount
of beta-glucan used in clinical trials has ranged from 2,900 to 15,000 mg per day. For
enhancing immune function, an effective amount
has not yet been determined due to the lack of studies in this application. However,
manufacturers of beta-glucan products usually recommend between 50 and 1,000 mg daily (to be
taken on an empty stomach), although some products contain as much as 500 mg per capsule.
Are there any side effects or interactions?
No side effects have been reported.
At the time of writing, there were no well-known drug interactions
with beta-glucan.